Chemomechanical coupling and multi-scale motility of molecular motors
Prof. Reinhard Lipowsky, MPI Potsdam
A unified description of all single-motor experiments is provided by a network representation based on the different nucleotide states of the motor. This representation also reveals novel balance conditions that provide relations between the kinetic and the thermodynamic parameters of the motors. The single motor properties are then used to develop a theoretical description for the cooperative behavior of motor teams or large motor ensembles.
The latter behavior includes uni-directional and bi-directional transport of cargo particles by small teams of motors as well as pattern formation and phase transitions in motor traffic.